Endocrine Abstracts

Introduction: Klinefelter Syndrome (KS) is related to late puberty and infertility. Early puberty in KS is a rare occurrence; a case of early puberty in KS is presented.Case report: A 10-year old boy, diagnosed with KS (47,XXY) during investigations for learning difficulties, was referred to the endocrine clinic with a history of facial acne since the age of 8 years. His examination showed pubic hair (stage 3) with testicular volume 4–5 ml on both s...

Introduction: HbA1c levels are used as objective long-term measure of glycaemic control in patients with type 1 diabetes mellitus (T1DM). Regular HbA1c measurement helps us to formulate the management and education to the patients and carers. But, in rare cases, it might not prove reliable, as in our case report.Case report: A 4 years old girl with known T1DM and autoimmune hyperthyroidism, had mitral valve repair for mitral valve regurgitation. She was ...

Background: WHO has recommended that adults of South Asian (SA) ethnicity need to have lower body mass index (BMI) cut-off to define overweight and obesity compared to White Caucasians (WC). The background for this is the increasing evidence that obesity-related morbidities are much higher at a lower BMI among SA compared to WC adults.Objective: The aim of our study was to evaluate differences in measures of insulin sensitivity amongst children and adole...

Introduction: Diabetic neuropathy is often a late manifestation of diabetes. Moreover its incidence in the paediatric age group is very rare. We present here a case of motor neuropathy as a first presenting feature of Type 1 diabetes mellitus.Case Report: A fourteen-year-old girl presented with right foot drop, which had progressively worsened over the last ten days. There was no other CNS or systemic involvement. Parents denied any history of pain, para...

Background: Conventional treatment for chronic hypoparathyroidism (CHP) is Vitamin-D analogues and calcium supplementation, not replacement of lacking hormone, as done in other hormone-deficiency states.Objectives: Retrospective evaluation of CHP management in line with European Society of Endocrinology Guideline was undertaken, to assess adequacy of calcium-homeostasis and morbidity.Methodology: Retrospective case-note and electro...